Effectiveness and safety of prenatal valacyclovir for congenital cytomegalovirus infection

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Prenatal Diagnosis of Congenital Cytomegalovirus Infection

We report here the results of a study on the prenatal diagnosis of congenital cytomegalovirus (CMV) infection. The study was carried out by both PCR and virus isolation from amniotic fluid (AF) for 82 pregnant women at risk of transmitting CMV for the detection of (i) seroconversion to CMV immunoglobulin G (IgG) positivity during the first trimester of pregnancy, (ii) symptomatic CMV infection ...

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Prenatal diagnosis of congenital cytomegalovirus infection.

OBJECTIVE To assess prospectively the diagnostic reliability and prognostic significance of prenatal diagnosis of cytomegalovirus (CMV) infection. METHODS One hundred ten pregnant women (four with twin pregnancies) with a risk of congenital CMV infection were investigated. Prenatal diagnosis was carried out by amniocentesis and fetal blood sampling (n = 75) or amniocentesis alone (n = 35). Se...

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Immunotherapy for congenital cytomegalovirus infection.

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Congenital cytomegalovirus virus infection.

A 14 months old male child with psychomotor retardation and hypotonia is reported, where computerized axial tomography revealed multiple calcification and ventriculomegaly secondary to cortical atrophy. Investigation suggested the diagnosis of cytomegalovirus infection. Importance of early diagnosis is emphasized as the potential long term sequelae can be prevented or reduced markedly with avai...

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[Congenital cytomegalovirus infection].

Cytomegalovirus (CMV) belongs to the herpesvirus family. Its distribution is ubiquitous in man and many other mammals. CMV causes a typical cytopathic effect with enlargement of the cells that contain intranuclear and cytoplasmic inclusions. CMV is spread directly or by a contact with secretions. Nosocomial transmission can occur during blood transfusion or organ transplantation. Virus excretio...

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ژورنال

عنوان ژورنال: Italian journal of gynaecology & obstetrics

سال: 2023

ISSN: ['2385-0868']

DOI: https://doi.org/10.36129/jog.2022.s62